Can transcranial magnetic stimulation (TMS) facilitate language recovery in chronic global aphasia post-stroke? Evidence from a case study
Publication date: August 2020Source: Journal of Neurolinguistics, Volume 55Author(s): Anastasios M. Georgiou, Ioannis Phinikettos, Chrysa Giasafaki, Maria Kambanaros
We report a case of a 60-year-old right-handed woman with hypertension, hyperlipidemia, and hypothyroidism who presented with a three-week history of recurrent thunderclap headaches accompanied by photophobia, phonophobia, nausea, and vomiting. She reported one brief episode of slurred speech, expressive aphasia, right facial droop, and right hemiparesis suggestive of a TIA. Family history was remarkable for primary angiitis of the CNS (PACNS) in the mother. Neurologic examination was unremarkable. CT of the head was negative; CT angiography (CTA) of the head and neck suggested fibromuscular dysplasia in bilateral cervical...
We report on the feasibility of implementing such standardized assessments into routine clinical care via measures of adherence. We also report on initial analyses of the data within the database that provide insights into the opportunities to track change. This initiative highlights the feasibility of collecting clinical data using a standardized assessment measure across acute and inpatient rehabilitation care settings. Practice-based evidence may inform future research by contributing pilot data and systematic observations that may lead to the development of empirical studies, which can then feed back into clinical practice.
A 43-year-old male pet shop owner on leflunomide for seronegative rheumatoid arthritis presented locally with strange behavior and aphasia, preceded by flu-like symptoms and high fevers. Initial workup revealed cerebrospinal fluid lymphocytic pleocytosis (22 cells, 74% lymphocytes), for which he was started on empiric antimicrobial therapy. A brain MRI revealed extensive, bilateral ischemic strokes (Figure 1). A transesophageal echocardiogram (TEE) was negative. He was then transferred to our institution for further evaluation.
CONCLUSIONS: This systematic review tried to provide to the reader a complete overview of the literature of all possible different speech treatments for dysarthria after stroke. A correct protocol could permit to improve the communication and the quality of life of these subjects. PMID: 32434313 [PubMed - as supplied by publisher]
CONCLUSIONS: In the present cases, although ischemic stroke was serious and precluded surgical indication for ATAAD, carotid artery stenting before surgery for ATAAD resulted in good clinical outcomes. Performing carotid artery stenting before surgery for ATAAD is challenging but achievable, and is a valid treatment option depending on the individual cases. PMID: 32397860 [PubMed - as supplied by publisher]
342Objectives: Crossed cerebellar diaschisis (CCD) is a common incidental finding on 18F-FDG brain PET studies. This phenomenon has been commonly described in patients with stroke (1-7), but only few case reports or case series have described it in patients with neurodegenerative diseases (8-10). We assessed prevalence of CCD in a large cohort of patients with neurodegenerative diseases and investigated the relationship between CCD and cortical asymmetries of glucose metabolism, amyloid deposition (11C -PIB) and Tau burden (18F-Flortaucipir (FTP)). Methods: We included 76 healthy controls and 197 patients who underwent 18F...