The antilymphatic metastatic effect of hyaluronic acid in a mouse model of oral squamous cell carcinoma.

Conclusion: Our findings confirmed the establishment of a fast and reliable lymphatic metastatic mouse model of OSCC that can be used for investigating metastatic mechanisms and analyzing various antimetastasis strategies. An equally important discovery is the antimetastatic property of HA, which could provide a potential therapeutic strategy for OSCC.
PMID: 32186431 [PubMed - as supplied by publisher]

Source: Cancer Biology and Therapy - March 17, 2020 Category: Cancer & Oncology Authors: Chen H, Wang M, Qi M, Tian Z, Wu W, Yang J, Zhang M, Tang L, Tang X Tags: Cancer Biol Ther Source Type: research