Latent Tuberculosis in Hematopoietic Stem Cell Transplantation: Diagnostic and Therapeutic Strategies to Prevent Disease Activation in an Endemic Population

Latent tuberculosis infection (LTBI) is a global health problem estimated to affect at least one out of every four people in the world [1]. Recent changes in sociodemographic paradigms during the latter part of the 20th century, have made of LTBI an important clinical and socioeconomic challenge, particularly in developing countries [2,3]. Incidence of LTBI varies widely between geographical regions, ranging from 3.3 and 11.9 cases per 100,000 individuals in the United States and the European Union, respectively, to 100 cases per 100,000 individuals in Africa [4,5,6].
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: Original Article Source Type: research