Presence of hot flashes may predict success of hormone therapy

Hormones at menopause can help with sleep, memory, and more, but only when a woman also has hot flashes, find researchers at Helsinki University in Finland. Their study was published online in Menopause, the journal of The North American Menopause Society (NAMS).NAMS and 14 other leading women's health organizations agree that hormone therapy is acceptable at menopause for most women who are bothered by moderate to severe menopause symptoms. For women who aren't bothered by moderate to severe hot flashes, this study indicates that hormone therapy will not improve their quality of life.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Menopause Source Type: news

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Conclusions: We extend existing research by demonstrating that hormone therapy (HT) in subjective sleep cannot be fully explained by improvements in VMS bother or depressive symptoms. Research to examine the mechanism (s) underlying HT's effects on sleep would have public health significance for perimenopausal women and also advance our general understanding of the pathophysiology of impaired sleep.
Source: Menopause - Category: OBGYN Tags: Brief Report Source Type: research
Authors: Li C, Wang L, Sun X, Yang X Abstract A large number of menopausal women report sleep disturbances along with psychological, somatic and urogenital menopausal symptoms. The aim of this study was to evaluate the efficacy of menopausal hormonal therapy (MHT) in improving subjective sleep quality and the severity of menopausal symptoms. An institutional ethics committee approved this retrospective chart review of 342 women treated with MHT for menopausal symptoms. Standard 28-day MHT consisted of the oral administration of 2 mg estradiol daily for 14 days, followed by 2 mg estradiol and 10 mg dydrogesterone da...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
ConclusionFurther studies are needed to elucidate the nature of the association between menopause, sleep and persistent pain syndromes, such as FM, showing the role of hormone therapy in prospective placebo ‐controlled trials.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: REVIEW Source Type: research
Abstract During the menopausal transition, which begins four to six years before cessation of menses, middle-aged women experience a progressive change in ovarian activity and a physiologic deterioration of hypothalamic-pituitary-ovarian axis function associated with fluctuating hormone levels. During this transition, women can suffer symptoms related to menopause (such as hot flushes, sleep disturbance, mood changes, memory complaints and vaginal dryness). Neurological symptoms such as sleep disturbance, "brain fog" and mood changes are a major complaint of women transitioning menopause, with a signific...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
Objective: To compare sleep quality and fatigue between women with premature ovarian insufficiency (POI) receiving hormone therapy (HT) and women of the same age with preserved ovarian function. Methods: This was a cross-sectional study of 61 women with POI receiving HT (POI group) and 61 women with preserved ovarian function (control group) who were matched by age (±2 years). The Pittsburgh Sleep Quality Index (PSQI) and Chalder Fatigue Scale were used to assess sleep quality and fatigue. Apart from correlation analysis, the Mann-Whitney, chi-square, or Fisher test was used to compare the groups. Results: W...
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
Conclusions: Low-dose paroxetine is an effective treatment for vasomotor menopause symptoms, including hot flushes. PMID: 31480427 [PubMed - in process]
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
MONDAY, Aug. 5, 2019 -- Women with premature ovarian insufficiency (POI) receiving hormone therapy have poor sleep quality, according to a study published online July 8 in Menopause. Cristina Laguna Benetti-Pinto, M.D., Ph.D., from the University of...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
(The North American Menopause Society (NAMS)) Sleep disturbances are a frequent complaint of women in the menopause transition and postmenopause. A new study demonstrates that women with premature ovarian insufficiency (POI) who are receiving hormone therapy have poorer sleep quality and greater fatigue than women of the same age with preserved ovarian function. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS).
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
A Combined, Bioidentical, Oral, 17β-Estradiol and Progesterone Capsule for the Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause. Expert Rev Clin Pharmacol. 2019 Jul 08;: Authors: Archer DF, Bernick BA, Mirkin S Abstract Introduction: Many women seek treatment to alleviate menopausal vasomotor symptoms (VMS). Numerous women use combination compounded hormone therapy (CHT) to achieve the benefits of estrogen/progesterone for endometrial protection. TX-001HR is a combination of bioidentical 17β-estradiol (E2) and progesterone (P4) in a single capsule designed for continuous da...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Conclusion: These findings indicate that TBI differentially affects the levels of sex-steroid hormones in men and women patients. Plasma levels of testosterone could be a good candidate blood marker to predict recovery from unconsciousness after sTBI for male patients. Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is increasing in incidence (1). Patients with acute severe TBI (sTBI) often develop severe disorders of consciousness, i.e., coma, minimally conscious state or vegetative state. Although many patients may regain consciousness during the 1-month post-TBI p...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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