Addendum: Drospirenone (Slynd) - A New Progestin-Only Oral Contraceptive

Date: March 23, 2020 Issue #: 1594Summary: In our article onSlynd (Med Lett Drugs Ther 2020; 62:18), the drospirenone-only oral contraceptive, we mentioned that drospirenone has antiandrogenic activity that could improve acne and antimineralocorticoid activity that could cause hyperkalemia. We should have added that concurrent use of drospirenone with other drugs that increase potassium levels, such as the anti-androgen aldosterone receptor antagonist spironolactone (Aldactone, and generics), which is often used off-label for treatment of acne, can increase the risk of hyperkalemia.

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Source: The Medical Letter - March 13, 2020 Category: Drugs & Pharmacology Authors: admin Tags: Acne Aldactone Contraceptives Drospirenone Oral contraceptives Psyllium Slynd Spironolactone Source Type: research