The OX40 Axis is Associated with Both Systemic and Local Involvement in Atopic Dermatitis.

This study further shows, using immunofluorescence on skin biopsies, that OX40+ and OX40L+ cells are co-located within the dermis, indicating local activity of OX40/OX40L. Serum levels of sOX40 were associated with atopic diseases and, together, these results support that the OX40 system is important for chronic inflammation in AD skin.
PMID: 32176307 [PubMed - as supplied by publisher]

Source: Acta Dermato-Venereologica - March 15, 2020 Category: Dermatology Authors: Elsner JS, Carlsson M, Stougaard JK, Nygaard U, Buchner M, Fölster-Holst R, Hvid M, Vestergaard C, Deleuran M, Deleuran B Tags: Acta Derm Venereol Source Type: research