Acid reflux drugs linked to increased fracture risk in kids

(Wolters Kluwer Health) Proton pump inhibitors -- a widely used class of drugs used to treat acid reflux and related symptoms - may lead to an increased risk of fractures in children and adolescents, reports a study in the Journal of Pediatric Gastroenterology and Nutrition (JPGN). Official journal of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, JPGN is published by Wolters Kluwer.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

Related Links:

Lucid is focused on patients with gastroesophageal reflux disease, also known as chronic heartburn or acid reflux, who are at risk of developing esophageal cancer.
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
Lucid is focused on patients with gastroesophageal reflux disease, also known as chronic heartburn or acid reflux, who are at risk of developing esophageal cancer.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
When Joe Silverman developed Crohn’s disease at age 21, the symptoms started out mild. While the sight of blood in his stools initially freaked him out, what really bothered him was the frequent abdominal pain and bloating that occurred as his condition progressed to moderate and then severe. Dietary changes didn’t make a difference, so he began taking prescription oral anti-inflammatory drugs that are often used to treat certain bowel diseases, which alleviated but didn’t eliminate his discomfort. He started using prescription steroid suppositories to cope with flare-ups of the inflammatory bowel disease...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: news
AbstractDespite ongoing evolution in technique and a low mortality rate, clinicians may care for patients who suffer late complications (> 90 days of surgery) after bariatric surgery. Endoscopic techniques are used to identify and manage many of the late complications of the two most commonly performed bariatric surgeries: sleeve gastrectomy and Roux-en-Y gastric bypass. Stenosis at the incisura angularis and gastroesophageal reflux disease may occur in patients who have undergone a sleeve gastrectomy. Patients who underwent a Roux-en-Y gastric bypass can suffer marginal ulceration, gastrojejunal anastomotic stricture, ...
Source: Obesity Surgery - Category: Surgery Source Type: research
Nature, Published online: 22 September 2021; doi:10.1038/s41586-021-03933-1The transcriptional programs and chromatin accessibility changes that cause two related interneuronal subtypes to diverge from common developmental origins and acquire specialized properties are elucidated.
Source: Nature AOP - Category: Research Authors: Source Type: research
CONCLUSIONS: The rate of development of symptomatic GERD after successful H. pylori eradication is low over long-term follow-up and is easily controlled by vonoprazan therapy. However, patients with smoking habits, functional dyspepsia, hiatal hernia, or severe gastric atrophy should be followed carefully after eradication.PMID:34547219 | DOI:10.1080/00365521.2021.1975310
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
In this study, ethylenediaminetetraacetic acid (EDTA) disodium was first chosen as catalyst to convert psoralenoside (PO) to psoralen (PSO) for increasing the extraction yield of PSO. An efficient continuous system for synchronous transformation and extraction of PSO from fig leaves applying microwave-assisted EDTA disodium (MAE-EDTA) was developed. The optimal MAE-EDTA condition was obtained: EDTA disodium concentration of 0.07 mol·L-1, ethanol volume fraction of 56%, extraction time of 16 min, and extraction temperature of 70 °C by single factor experiments and response surface method (RSM). Under the optimal ...
Source: Natural Product Research - Category: Biochemistry Authors: Source Type: research
ConclusionThe results of this study indicate that esophageal clearance may affect the treatment outcome of LF. Based on the findings of MII-pH, the longest reflux time and the number of refluxes longer than 5  min were important factors influencing the therapeutic effect, whereas based on the HRM, the DCI value was most important.
Source: Surgery Today - Category: Surgery Source Type: research
Discussion: The transcriptomic gene expression patterns in the BEC model demonstrate evidence of a clear threshold in the progression of BE to malignancy. Catastrophic transcriptomic changes during a window period culminate in the commitment of the BE cells to a “point of no return,” and removal of ABS is not effective in preventing their malignant transformation. Discerning this “point of no return” during BE surveillance by tracking the GEPs has the potential to evaluate risk of BE progression and enable personalized clinical management.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
AbstractBackgroundBariatric surgery has been increasingly becoming popular due to the advancements in minimally invasive approaches and techniques. The aim of this study was to compare the long-term outcomes and clinical relevance of laparoscopic sleeve gastrectomy (LSG) and laparoscopic greater curvature plication (LGCP) in a matched controlled single-bariatric centre study.MethodsWe collected data from 163 patients who underwent either LSG or LGCP over a period of at least 5  years. The outcome parameters included body mass index (BMI) changes, causes of revision surgery, endoscopic findings and effects on obesity-r...
Source: Obesity Surgery - Category: Surgery Source Type: research
More News: Acid Reflux | Children | Gastroenterology | Gastroesophageal Reflux Disease | GERD | International Medicine & Public Health | Nutrition | Pediatrics | Study | USA Health