Impaired activation of Notch-1 signaling hinders repair processes of bronchial epithelial cells exposed to cigarette smoke.

In conclusion, cigarette smoke exposure, limiting Notch-1 signaling activation and hindering repair processes, amplifies injury processes in bronchial epithelial cells.
PMID: 32169443 [PubMed - as supplied by publisher]

Source: Toxicology Letters - March 9, 2020 Category: Toxicology Authors: Di Sano C, D'Anna C, Ferraro M, Chiappara G, Sangiorgi C, Di Vincenzo S, Bertani A, Vitulo P, Bruno A, Dino P, Pace E Tags: Toxicol Lett Source Type: research