Women with familial risk for breast cancer have an increased frequency of aldehyde dehydrogenase expressing cells in breast ductules.

CONCLUSION: In histologically normal breast tissue, we found a positive association between the frequency of ductular ALDH+ cells and several breast cancer risk factors, particularly family history of this disease, which supports previous evidence that ALDH plays a role in breast cancer.
PMID: 24188377 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - November 4, 2013 Category: Cancer & Oncology Authors: Isfoss BL, Holmqvist B, Jernström H, Alm P, Olsson H Tags: BMC Clin Pathol Source Type: research