Basal ganglia calcification.

[Basal ganglia calcification]. Rev Med Interne. 2020 Mar 09;: Authors: Auffray-Calvier E, Lintia-Gaultier A, Bourcier R, Aguilar Garcia J Abstract Calcifications of the basal ganglia are frequently seen on the cerebral CT scans and particularly in the globus pallidus. Their frequency increases physiologically with age after 50 years old. However, pathological processes can also be associated with calcium deposits in the gray nuclei, posterior fossa or white matter. Unilateral calcification is often related to an acquired origin whereas bilateral ones are mostly linked to an acquired or genetic origin that will be sought after eliminating a perturbation of phosphocalcic metabolism. In pathological contexts, these calcifications may be accompanied by neurological symptoms related to the underlying disease: Parkinson's syndrome, psychiatric and cognitive disorders, epilepsy or headache. The purpose of this article is to provide a diagnostic aid, in addition to clinical and biology, through the analysis of calcification topography and the study of different MRI sequences. PMID: 32165049 [PubMed - as supplied by publisher]
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research

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CONCLUSION: The limited amount of knowledge denotes the need for additional in vitro studies on the combination of rTMS and pharmacotherapy, which could be extended to in vivo studies and ultimately inform the design of clinical trials so as to improve the therapeutic management of patients with a wide array of neuropsychiatric disorders. PMID: 32418533 [PubMed - as supplied by publisher]
Source: CNS and Neurological Disorders Drug Targets - Category: Drugs & Pharmacology Authors: Tags: CNS Neurol Disord Drug Targets Source Type: research
Abstract NLC is a next-generation lipid nanocarrier which holds many advantages over other colloidal lipid carrier system like higher drug loading, better and controlled release and enhanced stability. Owing to the unique structural composition, i.e. crystallized solid and liquid lipid blend it offers excellent biocompatibility and higher permeation across physiological membranes like BBB. Moreover, the surface of NLC can be easily modified with target-specific ligands, proteins, peptides, etc. which makes it a potential candidate for brain targeting of CNS acting drugs. NLC has found various applications in treat...
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
Tracey Morait is the first author to be interviewed me since I moved my online presence to healthy, happy woman and she joins me today to share new about her latest book, Episode. She’s the author of 6 books, comes from Liverpool and is a fanatical football fan – who wouldn’t be coming from Liverpool! She now lives in Bristol with her husband. Tracey writes and self-publishes books for children and young adults between the ages of nine and sixteen and Keith designs the book covers. K&T Mitchell is their own small press. A 5 star review for my book on Amazon.co.uk. “I have read all of Tracey Morait&r...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Thursday Throng Writing YA Source Type: news
This study confers the discipline, frameworks, and methodologies used by different deep learning techniques to diagnose different human neurological disorders. Here, one hundred and thirty-six different articles related to neurological and neuropsychiatric disorders diagnosed using different deep learning techniques are studied. The morbidity and mortality rate of major neuropsychiatric and neurological disorders has also bee n delineated. The performance and publication trend of different deep learning techniques employed in the investigation of these diseases has been examined and analyzed. Different performance metrics ...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
CONCLUSION: Air pollution is associated with increased risk of certain common neurological disorders. More specific studies are needed to investigate the impact of seasonal haze on neurological conditions in Southeast Asia. PMID: 32200394 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - Category: General Medicine Authors: Tags: Ann Acad Med Singapore Source Type: research
Authors: Chayasirisobhon S Abstract Cannabis plant has the scientific name called Cannabis sativa L. Cannabis plant has many species, but there are three main species including Cannabis sativa, Cannabis indica and Cannabis ruderalis. Over 70 compounds isolated from cannabis species are called cannabinoids (CBN). Cannabinoids produce over 100 naturally occurring chemicals. The most abundant chemicals are delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD). THC is psychotropic chemical that makes people feel "high" while CBD is nonpsychotropic chemical. However, cannabinoid chemicals are not found only...
Source: Acta Neurologica Taiwanica - Category: Neurology Tags: Acta Neurol Taiwan Source Type: research
APPROACHES FOR ENCEPHALIC DRUG DELIVERY USING NANOMATERIALS: THE CURRENT STATUS. Brain Res Bull. 2019 Nov 29;: Authors: V AN Abstract Nanotechnology, the investigation of little structures, ranging from the size of 1 nm to 100 nm presents a breakthrough in the field of targeted drug delivery. The microvasculature in the human brain along with the blood brain barrier (BBB) offers high resistance to the entry of therapeutics agents and other substances in to the brain. Nanoparticles have certain advantages as high permeability, reactivity, surface area and quantum properties and it also me...
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research
CONCLUSIONS: In this review, biological and chemical knowledge of melatonin, its experimental effects, and the clinical impact on patients with neurological disorders were described. According to all of the beneficial results obtained from experimental and clinical trials, melatonin may have a prophylactic and therapeutic effect on neurological diseases. Strong collaboration between neurologists and health service policy makers is needed to encourage use of melatonin in the patients suffering from neurological diseases. Melatonin may be the solution we have been looking for. PMID: 31718830 [PubMed - as supplied by publisher]
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Abstract Purinergic signaling was proposed in 1972, after it was demonstrated that adenosine 5'-triphosphate (ATP) was a transmitter in nonadrenergic, noncholinergic inhibitory nerves supplying the guinea-pig taenia coli. Later, ATP was identified as an excitatory cotransmitter in sympathetic and parasympathetic nerves, and it is now apparent that ATP acts as a cotransmitter in most, if not all, nerves in both the peripheral nervous system and central nervous system (CNS). ATP acts as a short-term signaling molecule in neurotransmission, neuromodulation, and neurosecretion. It also has potent, long-term (trophic) ...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
Inder Puri, Govind Singh, Rajendra Kumar Acharya, Divya GoswamiAnnals of Indian Academy of Neurology 2019 22(4):373-376 New disability law called “Rights of Persons with Disabilities Act 2016” has been acted in 2016. The United Nations' Convention for Rights of Persons with Disabilities is the sole of this new act. Of the total 21 categories, three new neurological legal disability categories such as chronic neurological conditions, Parkinson disease (PD), and multiple sclerosis have been notified first time in the new act. The new guidelines have been notified in the year 2018 for evaluation and certifica...
Source: Annals of Indian Academy of Neurology - Category: Neurology Authors: Source Type: research
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