Biological and antibacterial properties of TiO2 coatings containing Ca/P/Ag by one-step and two-step methods.

Biological and antibacterial properties of TiO2 coatings containing Ca/P/Ag by one-step and two-step methods. Biomed Microdevices. 2020 Mar 12;22(2):24 Authors: Zhang L, Li B, Zhang X, Wang D, Zhou L, Li H, Liang C, Liu S, Wang H Abstract The porous TiO2 coatings containing Ca/P/Ag were separately prepared on titanium (Ti) surface by one-step (micro-arc oxidation) and two-step methods (micro-arc oxidation and cathodic deposition), and then their surface morphology, composition, biological and antibacterial properties were compared. The results showed that the porous coatings containing Ca/P/Ag achieved by different methods showed similar surface morphology and elemental composition, however, by one-step method, silver existed in the coating as silver phosphate, while in the coatings prepared by two-step method, silver existed as metallic silver. Although both coatings showed excellent antibacterial property (the antimicrobial rate is over 99.9%), the surface coating prepared by one-step method had a more suitable release curve of Ag. In addition, the surface coating prepared by one-step method also presented better biological property, which was due to its enhanced surface roughness and hydrophilicity. Combining with its easy operation and long-term antibacterial property, its prospect for clinical application is more promising. PMID: 32166408 [PubMed - in process]
Source: Biomedical Microdevices - Category: Biomedical Engineering Authors: Tags: Biomed Microdevices Source Type: research