Up-regulation of LIMK1 expression in prostate cancer is correlated with poor pathological features, lymph node metastases and biochemical recurrence.

In conclusion, LIMK1 was significantly up-regulated in PCa and positive lymph node specimens and correlated with lymph node metastasis and shortened BFS of PCa. The underlying molecular mechanism of LIMK1 in PCa should be further evaluated.
PMID: 32168432 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - March 12, 2020 Category: Molecular Biology Authors: Huang JB, Wu YP, Lin YZ, Cai H, Chen SH, Sun XL, Li XD, Wei Y, Zheng QS, Xu N, Xue XY Tags: J Cell Mol Med Source Type: research