Reversible redox-responsive 1H/19F MRI molecular probes.

Reversible redox-responsive 1H/19F MRI molecular probes.
Chem Commun (Camb). 2020 Mar 12;:
Authors: Chen H, Tang X, Gong X, Chen D, Li A, Sun C, Lin H, Gao J
Abstract
Herein we report a pair of redox-responsive manganese complexes Mn(iii)/(ii)-N,N'-bis(2-hydroxy-4-trifluoromethylbenzyl)ethylenediamine-N,N'-diacetate (HTFBED, L1), which are water soluble and biologically interconvertible, as reversible redox-responsive probes in 1H/19F MRI for detecting and imaging biological redox species, offering a means to access valuable redox information associated with various diseases.
PMID: 32163087 [PubMed - as supplied by publisher]

Source: Chemical Communications - March 11, 2020 Category: Chemistry Authors: Chen H, Tang X, Gong X, Chen D, Li A, Sun C, Lin H, Gao J Tags: Chem Commun (Camb) Source Type: research