Probiotic pickled turnip touted as ‘flu wonder cure’

Conclusion This simple experiment showed that giving a bacterial extract found in Japanese pickled turnip to mice, as a preventative treatment for flu, reduced some of the symptomatic effects of flu upon subsequent infection. Specifically, it lessened body weight loss and reduced declines in general health during a seven-day flu period. While the results are encouraging, it is too soon to roll out the red carpet and welcome a “new wonder cure” as both the headlines in the Daily Express and Mail Online suggest. For instance, mice given the Japanese pickle extract still experienced declines in body weight of approximately 20% by day seven and significant decreases in general health, so they certainly weren’t cured of flu completely. However, the symptoms were significantly milder than mice that didn’t receive the extract. Any new treatment that could potentially help those at higher health risk from severe flu infection, such as the very young, very old, or others with a weakened immune system, would be an important breakthrough. Currently available antiviral medications can only shorten the duration of a flu infection by around a day. However, it is far too early to say that this bacterial extract is the breakthrough the world is waiting for. This was a study in mice, so many further experiments confirming the findings are needed. Following these, and assuming they are successful, further experiments will be needed on humans and again if effective cli...
Source: NHS News Feed - Category: Consumer Health News Tags: Food/diet Medical practice Medication Swine flu Source Type: news

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In this study, aqueous suspensions of various active ingredients (A.I.s) were utilized to generate Engineered Water Nanostructures (EWNS) nano-sanitizers, containing the A.I. utilized to produced them (termed iEWNS). These iEWNS had nanoscale size, were loaded with ROS and contained the A.I. utilized to produce them. They were challenged with Influenza H1N1/PR/8 and Acinetobacter baumannii on surfaces and in air. The results indicate that a nanogram dose of A.I. is effective in producing significant inactivation in Influenza H1N1/PR/8 and Acinetobacter baumannii.
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
(MedPage Today) -- Four distinct types of anti-vaccination content seen in Facebook posts
Source: MedPage Today Public Health - Category: American Health Source Type: news
In this study, we developed a small interfering RNA generation system that expressed two different short hairpin RNAs (shRNAs) targeting the M gene of PEDV and SADS-CoV and the N gene of PDCoV, respectively. Our results demonstrated that simultaneous expression of these specific shRNA molecules inhibited expression of PEDV M gene, SADS-CoV M gene, and PDCoV N gene RNA by 99.7%, 99.4%, and 98.8%, respectively, in infected cell cultures. In addition, shRNA molecules significantly restricted the expression of M and N protein, and impaired the replication of PEDV, SADS-CoV, and PDCoV simultaneously. Taken together, this shRNAs...
Source: Antiviral Therapy - Category: Virology Source Type: research
Publication date: April 2019Source: Current Opinion in Virology, Volume 35Author(s): Rosemary Morgan, Sabra L KleinMales/men and females/women differ in the outcome of influenza A virus (IAV) infections, vaccination, and antiviral treatments. Both sex (i.e. biological factors) and gender (i.e. sociocultural factors) can impact exposure and severity of IAV infections as well as responses and outcomes of treatments for IAV. Greater consideration of the combined effects of sex and gender in epidemiological, clinical, and animal studies of influenza pathogenesis is needed.Graphical abstract
Source: Current Opinion in Virology - Category: Virology Source Type: research
Publication date: Available online 20 March 2019Source: Preventive Veterinary MedicineAuthor(s): Bin Cui, Zong Ping Liu, Jun Ke, Yi TianAbstractThe implementation of biosecurity measures among farmers is the first line of defense against highly pathogenic avian influenza (HPAI) on poultry farms. Yet much less is known about the association between HPAI outbreak information sources, farmers’ risk perception and their adoption of biosecurity behaviors (BBs). To bridge this gap, a survey (n = 426) was conducted to measure the relationship between these factors among poultry farmers in the Chinese provinces...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Retraction notice to "Activity of ultra-low doses of antibodies to gamma-interferon against lethal influenza A(H1N1)2009 virus infection in mice" [Antiviral Research 93 (2012) 219-224]. Antiviral Res. 2019 Apr;164:177 Authors: Tarasov SA, Zarubaev VV, Gorbunov EA, Sergeeva SA, Epstein OI PMID: 30885299 [PubMed - in process]
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
Publication date: Available online 20 March 2019Source: Molecular Phylogenetics and EvolutionAuthor(s): Elma H. Akand, Kevin.M. DownardAbstractA mass based phylonumerics approach is shown to be able to investigate the origins of the emergence of antiviral resistance mutations in influenza neuraminidase through a global view of mutational trends. Frequent ancestral and descendant mutations that precede and follow the manifestation of antiviral resistance mutations are identified in N2 neuraminidase. The majority occur in the head region around the active site and drive hydrophilicity changes, primarily through the incorpora...
Source: Molecular Phylogenetics and Evolution - Category: Molecular Biology Source Type: research
Publication date: Available online 20 March 2019Source: Journal of Theoretical BiologyAuthor(s): Aniruddha Deka, Samit BhattacharyyaAbstractCommunicable diseases are leading cause of child mortality in developing and under-developed countries. Public health ministries in states and country allocate a considerable amount of budget every year for vaccination campaigns to control infections. Even third-party agencies such as Gates Foundation, UNDP, GAVI, World Bank, WHO also allocate huge funds to under-developed and developing countries for vaccination programs and disease eliminations. However, economic constraints and curr...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9NJ00356H, PaperAmbrish Singh, Kashif Rahmani Ansari, Mumtaz Ahmad Quraishi, Savas Kaya, Priyabrata Banerjee The corrosion inhibition behavior of naphthoxazinone derivative namely 1-Phenyl-1,2-dihydro-naphtho[1,2-e][1,3]oxazin-3-one (PNO) on N80 steel in 3.5 wt.% NaCl solution saturated with carbon dioxide was evaluated using weight loss, electrochemical impedance spectroscopy... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
This study elicits the general public's view on how to balance these outcomes in funding decisions for vaccines. We performed an optimal design discrete choice experiment with partial profiles in a representative sample (N = 1499) of the public in the United Kingdom in November 2016. Using a panel mixed logit model, we quantified, for four different types of infectious disease, the importance of a person's age during disease, how disease was prevented—via direct vaccine protection or herd protection—and whether the vaccine induced side effects. Our study shows clear patterns in how the public values vaccina...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
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