Long-term scintigraphic and clinical follow up in patients with differentiated thyroid cancer and iodine avid bone metastases

Conclusion Despite of low CR rate (8.6%), most patients with DTC and iodine avid bone metastases had SD (46.2%) and long lived (88.2%). Adjunctive radiotherapy reduced PD and improved outcome. Males, extra thyroid extension and vascular invasion were bad prognostic factors.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research

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In conclusion, the present case is an extremely rare occurrence of simultaneous multiple RDMs from PTC as the initial presentation.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
This study investigated the role of ultrasound gray scale ratio (UGSR) for the differentiated diagnosis of malignant and benign thyroid nodules. Using the UGSR to assess the echo was obviously more objective and accurate than the echogenicity identified by the naked eyes. The UGSR can be used as an additional ultrasound parameter in the diagnosis of different ‐sized thyroid nodules. AbstractAt present, hypoechogenicity, as one of the clinically relevant features associated with suspicion of malignant thyroid disease, is affected by the variability of modules and the experience of sonographers, thus leading to unsatisfyin...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Conclusion: In papillary thyroid carcinoma I-131 post-ablation SPECT/CT scan detects cervical lymphadenopathy and predicts relapse by NM stage more accurately than WBS.
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
Abstract BACKGROUND: About 10% of thyroid cancers are medullary thyroid carcinoma (MTC) and can occur sporadically, familially and in the context of type II multiple endocrine neoplasia (MEN). Imaging plays a pivotal role in screening family members and in diagnosis. DIAGNOSTIC METHODS: Diagnosis is based on ultrasound (US), thyroid scintigraphy, serum calcitonin and carcinoembryonic antigen (CEA) as well as fine needle biopsy. High-resolution US is the most important imaging method for locoregional staging, combined with computed tomography (CT) of the mediastinum. Positron emission tomography (PET...
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research
CONCLUSION: This case highlights the importance of defining the US characteristics of rare variants of thyroid neoplasms, since an early diagnosis is decisive in defining the patient's prognosis. PMID: 31140157 [PubMed - as supplied by publisher]
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
Conclusion: If the thyroid nodule is detected with flouro-2-deoxy-D-glucose uptake, to differentiate benign nodule from malignant, cytological examination is noteworthy to diagnose the more aggressive type of thyroid nodule and also thyroid metastasis from primary cancer.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
ConclusionsSerum Tg is a useful biomarker for risk stratification and decision-making in the management of DTC. It is expected to be used more widely in NM practice.
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research
Conclusion: This case of thyroid bed PG supports the idea that PG reflects a cutaneous phenotype encompassed in the spectrum of systemic neutrophilic diseases. Endocrinologists should be aware that thyroid bed PG involvement is an albeit rare differential diagnosis to consider in patients who had undergone thyroid surgery, especially with a history of PG. Introduction Papillary thyroid carcinoma (PTC), the main variant of differentiated thyroid carcinoma (DTC), is the most common thyroid cancer, accounting for 70–80% of all thyroid carcinomas and occurring predominantly in women, generally with a good prognos...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
In conclusion, despite the low prevalence of IET and cervical EET, clinicians and radiologists should be aware of US characteristics of such lesions and of the necessity of confirmation of their benign character. Elastography is a useful tool to initially differentiate PTC and IET. However, due to the high risk of malignancy in thyroid lesions in children, similarity of US features of PTC and IET, and because of the possibility of malignancy in ET, only cytological evaluation provides definitive diagnosis and prevents, on one hand, unnecessary frequent diagnostic procedures and/or surgery and, on the other hand, missing ma...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
ConclusionsThese are the first descriptions of thyroid papillary carcinoma without preoperative FCH-PET identification. These clinical cases are contrary to recent publications showing a benefit of this examination in the diagnosis of thyroid cancers.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
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