Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases

Conditions:   Bone Metastases;   Bone Neoplasm;   Bone Lesion;   Bone Cancer;   Pain;   Cancer Induced Bone Pain;   Quality of Life;   Tumor;   Neoplasm Metastasis Interventions:   Radiation: External beam radiotherapy;   Procedure: MR-HIFU Sponsors:   UMC Utrecht;   Turku University Hospital;   Universitätsklinikum Köln;   University of Roma La Sapienza;   Istituto Ortopedico Rizzoli;   University of Bologna;   Isala Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

Related Links:

Authors: Thudium M, Bette B, Tonguc T, Ghaei S, Conrad R, Becher MU, Mücke M, Luechters G, Strunk H, Marinova M Abstract Introduction: High-intensity focused ultrasound (HIFU) for pancreatic cancer is a growing therapeutic field which has been proven to reduce cancer pain and provide a local tumor control additionally to standard palliative care. However, less is known about the multidisciplinary and especially anesthesiological management of HIFU treatment although an interdisciplinary approach is crucial for treatment success.Material and methods: Anesthesiological and radiological records of 71 HIFU-treated...
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
AbstractPurpose of ReviewTo describe several effective imaging-guided, minimally invasive treatments to relieve cancer-associated pain in oncologic patients. Clinical applications, technical considerations, and current controversies are addressed.Recent FindingsThe great variability in tumor subtype, location, and growth rates dictate the necessity for a tailored treatment approach. While opioids and radiotherapy may provide adequate relief for some patients, alternative minimally invasive procedures may augment theses more traditional treatments or even provide superior palliative relief. Recent image-guided percutaneous ...
Source: Current Oncology Reports - Category: Cancer & Oncology Source Type: research
Conditions:   Bone Metastases;   Bone Neoplasm;   Bone Lesion;   Bone Cancer;   Pain;   Cancer Induced Bone Pain;   Quality of Life;   Tumor;   Neoplasm Metastasis Interventions:   Radiation: External beam radiotherapy;   Procedure: MR-HIFU Sponsors:   UMC Utrecht;   Turku University Hospital;   Universitätsklinikum Köln;   University of Roma La Sapienza;   Istituto Ortopedico Rizzoli;   University of ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: With local ablative techniques an improvement in the quality of life and possibly the prognosis can be achieved in patients with unresectable pancreatic cancer; however, the latter aspect has to be viewed with caution due to a current lack of well-founded data. PMID: 31828387 [PubMed - as supplied by publisher]
Source: Der Chirurg - Category: Surgery Authors: Tags: Chirurg Source Type: research
To determine quality of life (QoL) outcomes after palliation of pain from bone metastases using magnetic resonance-guided high intensity focused ultrasound (MR-guided HIFU), measured using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C15-PAL and the QLQ-BM22 questionnaires.
Source: Clinical Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
ConclusionsHIFU appears to be an effective tool for pain palliation in advanced pancreatic cancer. Studies assessing treatment in patients with pancreatic adenocarcinoma are limited by factors such as small sample sizes and heterogeneity in clinical definitions and assessments. Prospective randomized and standardized studies are necessary to confirm the effectiveness of HIFU in relieving pain, and to evaluate for any potential impact on tumor control and patient survival.
Source: Journal of Therapeutic Ultrasound - Category: Radiology Source Type: research
CONCLUSION: Our study corroborates magnetic resonance-guided focused ultrasound as a feasible and safe modality as a primary, palliative treatment for painful bone metastases and contributes to the limited body of literature using magnetic resonance-guided focused ultrasound for this clinical indication. PMID: 27480322 [PubMed - as supplied by publisher]
Source: Technology in Cancer Research and Treatment - Category: Cancer & Oncology Authors: Tags: Technol Cancer Res Treat Source Type: research
In this study 20 patients with locally advanced inoperable pancreatic cancer and tumor-related pain were treated by US-guided HIFU (6 stage III, 12 stage IV according to UICC and 2 with local recurrence after surgery). Ablation was performed using the JC HIFU system (HAIFU, Chongqing, China) with an ultrasonic device for real-time imaging. Clinical assessment included evaluation of pain severity using validated questionnaires with particular attention to the pain sensation scale (SES) with its affective and sensory component and the numeric rating scale (NRS). RESULTS: The average pain reducti...
Source: Schmerz - Category: Anesthesiology Authors: Tags: Schmerz Source Type: research
More News: Cancer | Cancer & Oncology | High Intensity Focused Ultrasound Therapy | Hospitals | Pain | Palliative | Research | Ultrasound