Widespread Occurrence of a CYP51A Pseudogene in Calonectria pseudonaviculata.

In this study, we have analyzed the CYP51 paralogs for polymorphism in 26 genomes, representing geographically disparate populations of C. pseudonaviculata (n = 19) and C. henricotiae (n = 7), from the U.S., Europe, Asia, and New Zealand. The presence of a CYP51A pseudogene and lack of a functional CYP51A paralog in all C. pseudonaviculata genomes examined is a novel discovery for fungi and could have implications for the evolution of resistance to antifungal chemicals. PMID: 32158605 [PubMed]
Source: Mycobiology - Category: Biology Tags: Mycobiology Source Type: research