Phenotypic and molecular characterization of macrolide resistance mechanisms among Streptococcus pneumoniae isolated in Tunisia.
Conclusion. This study shows that macrolide resistance among S. pneumoniae isolated in Tunisia is mainly related to target site modification. Our observations demonstrate a high degree of genetic diversity and capsular types among strains resistant to macrolides. PMID: 32159507 [PubMed - as supplied by publisher]
Cordero, a 41-year-old Tony nominee, was initially hospitalized March 30 after developing pneumonia and later tested positive for the coronavirus.
Recently, the White House unveiled its ambitious plan to develop a coronavirus vaccine before year ’s end. While many immediately questioned the feasibility of this timeline, we worry that not enough attention has gone to a different but equally important concern: Once we have a vaccine that works, who around the world will actually get to use […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
[UCT] Researchers from the South African Tuberculosis Vaccine Initiative (SATVI) at the University of Cape Town (UCT), the Center for Global Infectious Disease Research - Seattle in the United States, and a large consortium of collaborators have developed a validated a new, simple blood-based test that has the potential to serve multiple functions in the fight against TB.
A researcher leading Thailand's push to manufacture a coronavirus vaccine says its aim is to make it cost-effective and accessible to Southeast Asia, and play a part in preventing a supply shortage globally.
The global novel coronavirus pandemic afflicting everyone is showing mixed signs of activity. In some countries it appears to be easing, while in others it appears to be experiencing a resurgence. It’s not at all clear when the pandemic will end, but it’s unlikely to do so before 2021. What has become increasingly clear is that the toll of the pandemic will impact more than the people who come down with COVID-19. The mental health impact of living with a pandemic is being mostly ignored — for now. But as the deaths continue to rise, we need to pay close attention to the cost of the pandemic’s reperc...
Let us help you appreciate exactly how much work must go into producing a new vaccine — and how much faster than usual it's going now.
Vaccine efforts have seen biotech’s valuation skyrocket, despite having no products on the market
Emergent resistance to antibiotics among Streptococcus pneumoniae isolates is a severe problem worldwide. Antibiotic resistance profiles for S pneumoniae isolates identified from pediatric patients in mainland China remains to be established. The clinical features, antimicrobial resistance, and multidrug resistance patterns of S pneumoniae were retrospectively analyzed at 10 children's hospitals in mainland China in 2016. Among the collected 6132 S pneumoniae isolates, pneumococcal diseases mainly occurred in children younger than 5 years old (85.1%). The resistance rate of S pneumoniae to clindamycin, erythromycin, tetr...
Conclusion: New carbapenem/βLI combinations may be viable alternatives to antimicrobial combination therapy as they displayed high efficacy in vitro and in vivo. Meropenem/Avibactam and Meropenem/Relebactam should be tested on larger sample sizes with different carbapenemases before progressing further in its preclinical development. Introduction Carbapenem resistant Gram-negative bacteria have been gradually increasing in prevalence in recent years. In the United States, the latest CDC Antibiotic Resistance Threat Report indicates that Carbapenem-Resistant Enterobacteriaceae (CREs) are responsible for 9,000 a...
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