Repurposed drug may be first targeted treatment for serious kidney disease

(Massachusetts General Hospital) A team led by Massachusetts General Hospital researchers is reporting that treatment with abatacept appeared to halt the course of focal segmental glomerulosclerosis in five patients, preventing four from losing transplanted kidneys and achieving disease remission in the fifth.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

Related Links:

What does this study tell us about the effects of HLA matching on the outcomes of deceased-donor kidney allografts?American Journal of Transplantation
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Transplantation Journal Article Source Type: news
By CHARLES SILVER and DAVID A.HYMAN Today THCB is happy to publish a piece reflecting the learnings from Charles Silver and David Hyman’s forthcoming book Overcharged: Why Americans Pay Too Much For Health Care, shortly to be published by the libertarian leaning Cato Institute. In subsequent weeks we’ll feature commentary from the right (Michael Cannon) and from the left (Andy Slavitt) about the book and its proposals. For now please give your views in the comments–Matthew Holt There are many reasons why the United States is “the most expensive place in the world to get sick.” In Par...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Economics OP-ED Cato Institute Charles Silver David A. Hyman Obamacare Overcharged Source Type: blogs
Doctors in Scotland believe a woman’s large tattoo on her leg may have been the cause of her unexplained inflammation and severe leg pain. The authors of a report on the woman’s case, published in BMJ Case Reports, say it is a reminder to physicians that they should be mindful of their patients’ tattoos if they encounter unusual and unexplained symptoms. The 31-year-old woman was suffering a condition called inflammatory myopathy, which affected her left leg and caused pain severe enough to disrupt her sleep. The woman had a double lung transplant in 2009, and was taking drugs to suppress her immune syst...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime tattoos Source Type: news
We describe the case of a 19-year-old patient who underwent an innovative reconstructive approach aimed at preserving viable limb length with sensory regeneration by using innervated tissue transfer after traumatic upper extremity amputation below the elbow. The forearm length was maximized by means of two neurovascular free flaps that formed a robust, functional, and versatile stump. The mechanism of this reconstruction originated from the practice of placing a double-innervated anterolateral thigh flap over a myocutaneous flap for covering protruding forearm bone shafts. This form of vascularized tissue transplantation h...
Source: European Journal of Plastic Surgery - Category: Cosmetic Surgery Source Type: research
A woman with cystic fibrosis and lung transplants suffered chronic pain for three years after she had a tattoo on her thighGetting a tattoo if you have a weakened immune system could put you at risk of complications, doctors have warned. The caution comes after a woman with cystic fibrosis and lung transplants developed thigh and knee pain after having body art inked on her leg.Doctors say those taking immunosuppressant drugs should take precautions if considering body art. These medicines are often given after an organ transplant or to treat autoimmune conditions such as Crohn ’s disease, lupus or rheumatoid arthrit...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Tattoos Medical research Immunology Biochemistry and molecular biology Health Cystic fibrosis Diabetes Source Type: news
Steven Featley, 23, from Stoke Ash in Suffolk, had his sixth liver transplant last year as part of a lifelong battle with rare condition biliary atresia, which he has had since he was six weeks old.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Image courtesy of Paragonix Technologies Many lungs being transported for transplant arrive in such bad shape that they cannot be used. Paragonix Technologies, Inc. aims to change that with SherpaLung, a specialized cooler that keeps lungs properly inflated and at the right temperature to survive an airplane trip. Paragonix Technologies just landed support from the Lung Transplant Foundation to continue developing and commercialize SherpaLung, the latest in its series of specialized organ transport carriers. Braintree, MA-based Paragonix launched similar devices for hearts and kidneys within the past several months, a...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News News Well Transplants Lung Transplant Foundation Paragonix Technologies Source Type: news
(MedPage Today) -- Recent developments of interest in cardiovascular medicine
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news
Conditions:   Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Acute Lymphoblastic Leukemia in Remission;   Acute Myeloid Leukemia in Remission;   Chronic Lymphocytic Leukemia;   Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Cytomegalovirus Positive;   D onor;   Hematopoietic Cell Transplantation Recipient;   Hodgkin Lymphoma;   Myelodysplastic Syndrome;   Myelodysplastic/Myeloproliferative Neoplasm;   Non-Hodgkin Lymphoma Intervention: ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Steven Featley, 23, from Stoke Ash in Suffolk, had his sixth liver transplant last year as part of a lifelong battle with rare condition biliary atresia, which he has had since he was six weeks old.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
More News: Abatacept | Health | Hospitals | International Medicine & Public Health | Orencia | Transplants | Urology & Nephrology