Prevalence of chronic chikungunya and associated risks factors in the French West Indies (La Martinique):  A prospective cohort study

by Antoine Bertolotti, Mar ême Thioune, Sylvie Abel, Gilda Belrose, Isabelle Calmont, Raymond Césaire, Minerva Cervantes, Laurence Fagour, Émilie Javelle, Catherine Lebris, Fatiha Najioullah, Sandrine Pierre-François, Benoît Rozé, Marie Vigan, Cédric Laouénan, André Cabié, the Chronic Chikungunya working group of Un iversity Medical Center of Martinique BackgroundThe chikungunya virus (CHIKV) is a re-emerging alphavirus that can cause chronic and potentially incapacitating rheumatic musculoskeletal disorders known as chronic chikungunya arthritis (CCA). We conducted a prospective cohort study of CHIKV-infected subjects during the 2013 chikungunya outbreak in Martinique. The aim of this study was to assess the prevalence of CCA at 12 months and to search for acute phase factors significantly associated with chronicity. Methodology/Principal findingsA total of 193 patients who tested positive for CHIKV RNA via qRT-PCR underwent clinical investigations in the acute phase (
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research