Enantioselective remote C-H activation directed by a chiral cation

We report here a strategy to render a common bipyridine ligand anionic and pair its iridium complexes with a chiral cation derived from quinine. We have applied these ion-paired complexes to long-range asymmetric induction in the desymmetrization of the geminal diaryl motif, located on a carbon or phosphorus center, by enantioselective C–H borylation. In principle, numerous common classes of ligand could likewise be amenable to this approach.
Source: ScienceNOW - Category: Science Authors: Tags: Chemistry reports Source Type: news