Crucial Gene Identification in Carotid Atherosclerosis Based on Peripheral Blood Mononuclear Cell (PBMC) Data by Weighted (Gene) Correlation Network Analysis (WGCNA).

CONCLUSIONS We detected 8 modules for the events group and 6 modules for the no-events group. The hub genes for modules and crucial genes of the DEG co-expression network were also identified. These genes might serve as potential targets for medical therapies and biomarkers for diagnosis and prognosis. Further experimental and biological studies are needed to elucidate the role of these crucial genes in the progression of carotid atherosclerosis. PMID: 32160184 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32160184?dopt=Abstract

Source: Medical Science Monitor - March 12, 2020 Category: Research Tags: Med Sci Monit Source Type: research