EEG Monitoring of the Epileptic Newborn

AbstractPurpose of ReviewAlthough differentiating neonatal-onset epilepsies from acute symptomatic neonatal seizures has been increasingly recognized as crucial, existing guidelines, and recommendations on EEG monitoring are mainly based on acute symptomatic seizures, especially secondary to hypoxic-ischemic encephalopathy. We aimed to narratively review current knowledge on neonatal-onset epilepsies of genetic, metabolic, and structural non-acquired origin, with special emphasis on EEG features and monitoring.Recent FindingsA wide range of rare conditions are increasingly described, reducing undiagnosed cases. Although distinguishing features are identifiable in some, how to best monitor and detect less described etiologies is still an issue. A comprehensive approach considering onset, seizure evolution, ictal semiology, clinical, laboratory, EEG, and neuroimaging data is key to diagnosis.SummaryPhenotypic variability prevents precise recommendations, but a solid, consistent method moving from existing published guidelines helps in correctly assessing these newborns in order to provide better care, especially in view of expanding precision therapies.
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research

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Publication date: September 2020Source: Epilepsy &Behavior, Volume 110Author(s): Christopher Ll Morgan, Stefan Varga, Wan Tsong, Sara Jenkins-Jones, Sarah Holden
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Conditions:   Resistant Epilepsy, Drug;   Adolescent Epilepsy;   Children Epilepsy;   Children and Adolescents With Resistant Epilepsies Interventions:   Drug: MGCND00EP1;   Drug: Placebo;   Diagnostic Test: ECG;   Diagnostic Test: EEG;   Diagnostic Test: Blood and urine collection Sponsor:   MGC Pharmaceuticals d.o.o Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To report progress, to identify gaps, and to plan epilepsy surveillance and research activities more effectively, the Centers for Disease Control and Prevention (CDC) Epilepsy Program has summarized findings from selected CDC-supported surveillance and epi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Abstract SUMMARYTaenia solium neurocysticercosis (NCC) is endemic in most of the world and contributes significantly to the burden of epilepsy and other neurological morbidity. Also present in developed countries because of immigration and travel, NCC is one of few diseases targeted for eradication. This paper reviews all aspects of its life cycle (taeniasis, porcine cysticercosis, human cysticercosis), with a focus on recent advances in its diagnosis, management, and control. Diagnosis of taeniasis is limited by poor availability of immunological or molecular assays. Diagnosis of NCC rests on neuroimaging finding...
Source: Clinical Microbiology Reviews - Category: Microbiology Authors: Tags: Clin Microbiol Rev Source Type: research
Conditions:   Resistant Epilepsy, Drug;   Adolescent Epilepsy;   Children Epilepsy;   Children and Adolescents With Resistant Epilepsies Interventions:   Drug: MGCND00EP1;   Drug: Placebo;   Diagnostic Test: ECG;   Diagnostic Test: EEG;   Diagnostic Test: Blood and urine collection Sponsor:   MGC Pharmaceuticals d.o.o Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Epilepsy death rates are still high among young adults and have not declined over time despite treatment advances, researchers say.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
NEUROSURGERY CLINICS OF NORTH AMERICA
Source: Neurosurgery Clinics of North America - Category: Neurosurgery Authors: Source Type: research
The notion of paradigm shifts in science was introduced in 1962 by the American physicist and philosopher Thomas Kuhn, describing a set of fundamental changes in the basic concepts, and subsequently, practices, of a scientific discipline. During the last decades, the field of epilepsy surgery in the United States has been through what Kuhn termed a revolutionary period; a period during which a paradigm shift in the way we comprehend and address surgically treatable epilepsies is taking place within our scientific and clinical community.
Source: Neurosurgery Clinics of North America - Category: Neurosurgery Authors: Source Type: research
The need to emphasize the network concept arises from the fact that the traditional surgical philosophy in American epilepsy centers has prioritized an electrical-anatomic, focus-oriented approach. In contrast, the stereoelectroencephalography philosophy focuses on using electrophysiology to determine the regions of cortex generating the clinical manifestation of the seizure. Viewing epilepsy surgery as network surgery enables optimal consideration of decisions related to the need for and method of intracranial monitoring, potential role of subcortical structures in seizure organization and propagation, upfront use of comb...
Source: Neurosurgery Clinics of North America - Category: Neurosurgery Authors: Source Type: research
This article discusses functional electrical stimulation in adults and children for different functional modalities.
Source: Neurosurgery Clinics of North America - Category: Neurosurgery Authors: Source Type: research
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