Clinical outcomes and Toxicity profile with IMRT or Brachytherapy boost in oropharyngeal malignancies: A Randomized, open label study

Radical radiation therapy in oropharyngeal malignancies have a significant toxicity especially in relation to dose to dysphagia aspiration related structures (DARS), mucositis and aspiration which leads to prolonged overall treatment times, thereby, having an impact on survival outcomes. Interstitial Brachytherapy (ISBT) has significant role in reducing these toxicities, however, literature comparing Intensity modulated radiation therapy (IMRT) with Brachytherapy boost is lacking. Our study looks in to the clinical outcomes and toxicity profile while comparing the two treatment modalities.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: K. Kian Ang, MD, PhD, FASTRO, Commemorative Plenary Session Source Type: research