A Ventriculoperitoneal Shunt Infection Successfully Treated with Intraventricular Coadministration of Tigecycline and Colistin

Klin Padiatr 2020; 232: 70-72 DOI: 10.1055/a-1108-1699Hemophagocytic lymphohistiocytosis (HLH) is a systemic inflammatory disorder characterized by uncontrolled histiocytic proliferation, hemophagocytosis, macrophage activation, and up-regulation of inflammatory cytokines (Grom AA., Current opinion in rheumatology 2003; 15: 587–590). HLH is usually divided into two types: primary (familial) HLH and secondary (reactive) HLH. Primary HLH is associated with primary immune deficiencies in which specific gene mutations play an important role, such as perforin defects. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Klinische Padiatrie - Category: Pediatrics Authors: Tags: Short Communication Source Type: research