Use of an Online Breast Cancer Risk Assessment and Patient Decision Aid in Primary Care Practices

Journal of Women's Health, Ahead of Print.
Source: Journal of Women - Category: OBGYN Authors: Source Type: research

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Authors: Gomes I, de Almeida BP, Dâmaso S, Mansinho A, Correia I, Henriques S, Cruz-Duarte R, Vilhais G, Félix P, Alves P, Corredeira P, Barbosa-Morais NL, Costa L, Casimiro S Abstract The role of RANKL-RANK pathway in progesterone-driven mammary carcinogenesis and triple negative breast cancer tumorigenesis has been well characterized. However, and despite evidences of the existence of RANK-positive hormone receptor (HR)-positive breast tumors, the implication of RANK expression in HR-positive breast cancers has not been addressed before. Here, we report that RANK pathway affects the expression of cel...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
In conclusion, results showed that the root extract possess the highest cytotoxicity among all other tested extracts toward both breast cancer cell lines (MCF-7 and MDA MB-231). PMID: 32479012 [PubMed - in process]
Source: Journal of Environmental Pathology, Toxicology and Oncology - Category: Environmental Health Tags: J Environ Pathol Toxicol Oncol Source Type: research
Authors: Zhang H, Lv P, Xiao Z, Jothi EA, Yang J Abstract Breast cancer is a widespread disease that affects women globally. Diagnostic processes and remedial approaches to breast carcinogenesis have improved in recent decades, but continuous survival of patients with breast carcinogenesis is still lacking due to increased cell proliferation. The aim of the present work is to explore the anticell proliferative effects of nobiletin (NOB) against 7,12-dimethylbenz[a]anthracene (DMBA)-treated mammary tumorigenesis in rats. We stimulate mammary carcinogenesis using oral gavage of DMBA (25 mg/kg body weight) mixed with ...
Source: Journal of Environmental Pathology, Toxicology and Oncology - Category: Environmental Health Tags: J Environ Pathol Toxicol Oncol Source Type: research
(Wiley) Outdoor light at night was linked to a higher risk of breast cancer in a study published in the International Journal of Cancer.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(Wiley) A new BJS (British Journal of Surgery) study indicates that breast cancer surgery is safe for patients who are older than 70 years of age, but age can influence the decision to undergo surgery.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Publication date: Available online 1 June 2020Source: Seminars in Cancer BiologyAuthor(s): Dipta Sengupta, Moonmoon Deb, Swayamsiddha Kar, Nibedita Pradhan, Sabnam Parbin, R. Kirtana, Suraj P. Singh, S.G. Suma, Niharika, Ankan Roy, Saumen Manna, Priyanka Saha, Priyanka Chakraborty, Soumya Dash, Chahat Kausar, Samir Kumar Patra
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
British Journal of Cancer, Published online: 03 June 2020; doi:10.1038/s41416-020-0873-zHuman Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcription
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
British Journal of Cancer, Published online: 03 June 2020; doi:10.1038/s41416-020-0909-4Phase 2 study of cabazitaxel as second-line treatment in patients with HER2-negative metastatic breast cancer previously treated with taxanes—a Hellenic Cooperative Oncology Group (HeCOG) Trial
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
In conclusion, Timo AIII is potent as a compound or leading compound for further drug development while still needs in-depth studies.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsThe HRD-high phenotype of AYA breast cancer patients can be deduced from genomic and pathological factors that are routinely examined in the oncology clinic, irrespective of germlineBRCA1/2 mutations.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
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