Primary immunodeficiencies and their associated risk of malignancies in children: an overview

Conclusion: The awareness of the association between several primary immunodeficiencies and cancer is crucial to provide the best care for these patients.What is Known:•Patients with primary immunodeficiency have an increased risk of malignancy. The type of malignancy is highly dependent on the specific primary immunodeficiency disorder.What is New:•Survival in patients with primary immunodeficiency disorders has been improving, and conversely also their lifetime risk of malignancy.•International collaboration and multinational registries are needed to improve our knowledge and therapeutic strategies.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research