Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task

ConclusionsThese experiments reveal that both α7nAChR and NMDAR activity are necessary for normal WM accuracy. They provide substantive new support for the therapeutic potential of positive modulators at these two receptor sites in SZ and other major brain diseases.
Source: Psychopharmacology - Category: Psychiatry Source Type: research