Propofol Causes Consciousness Loss by Affecting GABA-A Receptor in the Nucleus Basalis of Rats.

Conclusions: The unilateral NB lesion increased the recovery time and FC delta power, and the NB region might be involved in the emergence after propofol administration. Propofol plays a crucial role for causing conscious loss by affecting GABA-A receptor in NB. PMID: 32148565 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32148565?dopt=Abstract

Source: Behavioural Neurology - March 11, 2020 Category: Neurology Authors: Xing Y, Li K, Jiao Y, Li Z Tags: Behav Neurol Source Type: research