Association between IL-17A and IL-17F gene polymorphism and susceptibility in inflammatory arthritis: A meta-analysis.

CONCLUSION: IL-17F gene rs763780 C allele confers increased risk of inflammatory arthritis in Caucasians; IL-17A gene rs2275913 G allele are protective for OA susceptibility in Mongolians. More well-designed studies with larger sample size are needed to elucidate the role of IL-17A gene rs2275913 G allele in inflammatory arthritis, especially AS.
PMID: 32146336 [PubMed - as supplied by publisher]

Source: Clinical Immunology - March 4, 2020 Category: Allergy & Immunology Authors: Shao M, Xu S, Yang H, Xu W, Deng J, Chen Y, Gao X, Guan S, Xu S, Shuai Z, Pan F Tags: Clin Immunol Source Type: research