585  nm light-emitting diodes inhibit melanogenesis through upregulating H19/miR-675 axis in LEDs-irradiated keratinocytes by paracrine effect

With the recognition of potential benefits of photobiomodulation (PBM) and the development of light-emitting diodes (LEDs), non-thermal phototherapy with the application of medical LEDs devices has been used over the last decade [1], from promoting tissue repair [2], decreasing inflammation[3], photorejuvenation[4], relieving acne vulgaris[5] and decreasing erythema and dermatitis[6]. LEDs phototherapy has also been documented in relieving hyperpigmentation in clinical practice, suggesting the effect of downregulating melanogenesis[7].

Source: Journal of Dermatological Science - March 9, 2020 Category: Dermatology Authors: Shanglin Jin, Li Chen, Zhongyi Xu, Xiaoxue Xing, Chengfeng Zhang, Leihong Xiang Tags: Original article Source Type: research