Metabolic syndrome and psoriatic arthritis: considerations for the clinician.

Metabolic syndrome and psoriatic arthritis: considerations for the clinician. Expert Rev Clin Immunol. 2020 Mar 09;: Authors: Caso F, Chimenti MS, Navarini L, Ruscitti P, Peluso R, Girolimetto N, Del Puente A, Giacomelli R, Scarpa R, Costa L Abstract Introduction: Metabolic Syndrome (MetS) is strictly interconnected with systemic inflammation and increased evidence have described a close link between this condition and Psoriatic Arthritis (PsA).Areas covered: This review summarizes main studies exploring clinical aspects and prevalence of MetS in PsA cohorts. Further, there is accumulating evidence showing shared inflammatory pathways between MetS, its components and PsA.Expert opinion: The high prevalence of MetS in PsA highlights the need of screening, evaluation and close monitoring of MetS and its components (namely, diabetes mellitus, obesity, hypertension, and dyslipidemia) in psoriatic patients.Further studies should focus on the pathogenetic link between MetS and PsA. More studies are required to identify appropriate algorithms for the assessment and management of MetS in PsA patients. PMID: 32149545 [PubMed - as supplied by publisher]
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research