Taste masking of water ‐soluble drug by solid lipid microspheres: a child‐friendly system established by reversed lipid‐based nanoparticle technique
ConclusionsAtomoxetine hydrochloride ‐reversed lipid‐based nanoparticle‐solid lipid microsphere exhibited excellent taste‐masking effect with negligible leakage in the oral cavity environment and thorough collapse upon lipase stimulation, simultaneously enhancing the bioavailability of ATX. The study paves a new way to efficien tly mask the undesirable taste of some water‐soluble drugs.
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Yadan Zhang,
Liao Shen,
Tao Wang,
Haiyan Li,
Ri Huang,
Zhen Zhang,
Yongan Wang,
Dongqin Quan Tags: Research Paper Source Type: research
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