The biofilm ‐associated bacterial infections unrelated to indwelling devices

AbstractBiofilms are microbial communities established in the self ‐produced extracellular substances that include up to 80% of associated microbial infections. During biofilm formation, bacterial cells shift from the planktonic forms to aggregated forms surrounded by an extracellular polymeric substance. The bacterial biofilm shows resistance against immune reac tions as well as antibiotics and is potentially able to cause disorders by both device‐related and nondevice‐related infections. The nondevice‐related bacterial biofilm infections include dental plaque, urinary tract infections, cystic fibrosis, otitis media, infective endocarditis, tonsilliti s, periodontitis, necrotizing fasciitis, osteomyelitis, infectious kidney stones, and chronic inflammatory diseases. In this review, we will summarize and examine the literature about bacterial biofilm infections unrelated to indwelling devices.

Source: IUBMB Life - March 9, 2020 Category: Research Authors: Rasoul Mirzaei, Rokhsareh Mohammadzadeh, Mohammad Yousef Alikhani, Mohammad Shokri Moghadam, Sajad Karampoor, Sima Kazemi, Alireza Barfipoursalar, Rasoul Yousefimashouf Tags: CRITICAL REVIEW Source Type: research