Digital Heart Model will Help Predict Future Heart Health

In recent times, researchers have increasing found that the power of computers and artificial intelligence is enabling more accurate diagnosis of a patient's current heart health and can provide an accurate projection of future heart health, potential treatments and disease prevention. Now in a paper published in European Heart Journal, researchers from King's College London, leading the Personalised In-Silico Cardiology consortium, show how linking computer and statistical models can improve clinical decisions relating to the heart.
Source: eHealth News EU - Category: Information Technology Tags: Featured Research Research and Development Source Type: news

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The absence of alloantibodies is a feature of transplantation tolerance. Although the lack of T cell help has been evoked to explain this absence, herein we provide evidence for B cell–intrinsic tolerance mechanisms. Using a murine model of heart tolerance, we showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies. We inferred that tolerant alloreactive B cells retained their ability to sense alloantigen because they continued to drive T cell maturation into CXCR5+PD-1+ T follicular helper cells. Unexpectedly...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Authors: den Exter PL, Beeres SLMA, Eikenboom J, Klok FA, Huisman MV Abstract INTRODUCTION: The treatment options for advanced heart failure patients drastically changed with the introduction of left ventricular assist devices (LVADs), either as bridge to transplant or as destination therapy for patients ineligible for transplant. Despite major benefits in terms of survival, functional status and quality of life, managing patients with LVADs comes with several challenges. The most significant challenge is balancing between the risks of thrombotic and bleeding complications. AREAS COVERED: The present review des...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
It’s been enough for a bit, isn’t it? For three months now, there has been little space in the world for any other kind of news. That is, news without the word ‘coronavirus’. But there was innovation, there is excitement and, well, even some weird (although useful!) inventions that appeared while the world has been in lockdown. So here’s an outlook on such news, all, promise, without that particular C-word. Hospitals have been facing great challenges recently. But they are on the verge of a new era that brings better care and more focus on the patient. This is a trend we have been talking a...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Robotics Telemedicine & Smartphones Virtual Reality amazon diabetes smart contact lens Stanford University pharmacies Fitbit fitness trackers genome sequencing diabetes management genomic data 5G robot Source Type: blogs
Zoltán Kálmán is Permanent Representative of Hungary to the Rome-based UN agencies (FAO, IFAD, WFP). He was President of the WFP Executive Board in 2018.By Zoltán KálmánROME, May 26 2020 (IPS) Hunger and food insecurity continue to rise. The official 2019 statistics refer to 821 million people suffering from hunger all over the world. According the recently launched Global Report on Food Crises, there are further 135 million people facing crisis levels of hunger or worse. WFP estimates that due to the impacts of COVID19, additional 130 million people could be pushed to the brink of...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Aid Armed Conflicts Climate Change Economy & Trade Food & Agriculture Food Sustainability Global Headlines Health Humanitarian Emergencies Inequity Poverty & SDGs TerraViva United Nations Source Type: news
Post-lung transplantation (post-LTx) progressive chronic kidney disease (CKD) is associated with increased morbidity and mortality.1 Comorbidities and cotreatments, and post-LTx medical complications, including acute kidney injury (AKI), are associated with an increased risk for subsequent CKD development.2 However, among the several risk factors for post-LTx CKD development, pre-transplant renal function plays a key role.3
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Research Correspondence Source Type: research
Implantable mechanical circulatory support (MCS) devices are used in patients with progressive heart failure either as destination therapy or a bridge-to-transplant. Left ventricular assist devices (LVAD) have become commonplace with development of continuous flow platforms. LVADs are effective in selected patients and improve quality of life and reduce mortality.1 However, patients with severe biventricular dysfunction or anatomical contraindications such as small or non-dilated ventricles (i.e.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research
AbstractPercutaneous biventricular assist devices (BiVAD) are a recently developed treatment option for severe cardiogenic shock. This systematic review sought to identify indications and outcomes of patients placed on percutaneous BiVAD support. An electronic search was performed to identify all appropriate studies utilizing a percutaneous BiVAD configuration. Fifteen studies comprising of 20 patients were identified. Individual patient survival and outcomes data were combined for statistical analysis. All 20 patients were supported with a microaxial LVAD, 12/20 (60%) of those patients were supported with a microaxial (RM...
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
Psychologists say anxiety and uncertainty prompt irrational decisions — like turning down a transplant when an organ becomes available.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Transplants Emergency Medical Treatment Coronavirus (2019-nCoV) Liver Fear (Emotion) Anxiety and Stress Cancer Heart your-feed-science your-feed-healthcare Source Type: news
This study, for instance, attributes a patient’s waitlist/transplant outcome to the very last dialysis facility the patient was associated with.  In epidemiology speak, this means the causal inference authors are trying to draw between for-profit status and good transplant outcomes is subject to time-varying confounding. As an example, if one is seeking an association between testosterone levels and risk of a heart attack, using the last testosterone level available would be a poor way of doing this study because testosterone levels are known to vary over time. The same applies to dialysis facilities. Patie...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Medical Practice Physicians Eric Weinhandl JAMA medical research public health Public Policy public policy research Source Type: blogs
Condition:   Left Ventricular Dysfunction Intervention:   Device: Use of Eko DUO electronic stethoscope Sponsor:   Eko Devices, Inc. Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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