Achieving 10 ps coincidence time resolution in TOF-PET is an impossible dream.

Achieving 10 ps coincidence time resolution in TOF-PET is an impossible dream.
Med Phys. 2020 Mar 06;:
Authors: Schaart DR, Ziegler S, Zaidi H
Abstract
A number of hardware and software developments in PET instrumentation during the last two decades have enabled improved localization of the position of annihilation along the line of response through precise measurement of the difference between the arrival times of the two annihilation photons. This concept is referred to as time-of-flight (TOF) PET and is implemented virtually on almost all commercial PET scanners. One limitation of this technology is the limited precision in the localization of the annihilation point owing to inherent uncertainty in the detector blocks and readout electronics which introduces some ambiguity in the photon arrival times.
PMID: 32141611 [PubMed - as supplied by publisher]

Source: Nuklearmedizin - March 5, 2020 Category: Radiology Authors: Schaart DR, Ziegler S, Zaidi H Tags: Med Phys Source Type: research