Optimum interval time of programmed intermittent epidural bolus of ropivacaine 0.08% with sufentanyl 0.3 μg/mL for labor analgesia: a biased-coin up-and-down sequential allocation trial.

CONCLUSION: With a fixed 10 mL dose of ropivacaine 0.08% with sufentanyl 0.3 μg/mL, the optimal PIEB interval is about 42 min. Further studies are warranted to define the efficacy of this regimen throughout all stages of labor.
TRIAL REGISTRATION: Chinese Clinical Trial Registry, ChiCTR1900022199; http://www.chictr.org.cn/com/25/historyversionpuben.aspx?regno=ChiCTR1900022199.
PMID: 32142491 [PubMed - as supplied by publisher]

Source: Chinese Medical Journal - March 4, 2020 Category: General Medicine Authors: Zhou SQ, Wang J, Du WJ, Song YJ, Xu ZD, Liu ZQ Tags: Chin Med J (Engl) Source Type: research