Curcumin augments therapeutic efficacy of TRAIL-based immunotoxins in leukemia.

CONCLUSION: Overall, our results suggest that curcumin potentiates TRAIL-induced apoptosis through modulation of death receptors and anti-apoptotic proteins which significantly enhances the therapeutic efficacy. PMID: 32141025 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32141025?dopt=Abstract

Source: Pharmacological Reports - March 4, 2020 Category: Drugs & Pharmacology Authors: Surapally S, Jayaprakasam M, Verma RS Tags: Pharmacol Rep Source Type: research