Synthesis, molecular modelling and biological activity of some pyridazinone derivatives as selective human monoamine oxidase-B inhibitors.

CONCLUSION: It was concluded that 4b is possibly recommended as a promising nominee for the design and development of new pyridazinones which can be used in the treatment of neurological diseases.
PMID: 32144745 [PubMed - as supplied by publisher]

Source: Pharmacological Reports - March 5, 2020 Category: Drugs & Pharmacology Authors: Özdemir Z, Alagöz MA, Uslu H, Karakurt A, Erikci A, Ucar G, Uysal M Tags: Pharmacol Rep Source Type: research