MiR-328-3p inhibits cell proliferation and metastasis in colorectal cancer by targeting Girdin and inhibiting the PI3K/Akt signaling pathway.

In conclusion, miR-328-3p may inhibit proliferation and metastasis of CRC cells by targeting Girdin and inactivating the PI3K/Akt signaling pathway. MiR-328-3p may be a novel target in cancer therapy.
PMID: 32142853 [PubMed - as supplied by publisher]

Source: Experimental Cell Research - March 2, 2020 Category: Cytology Authors: Pan S, Ren F, Li L, Liu D, Li Y, Wang A, Li W, Dong Y, Guo W Tags: Exp Cell Res Source Type: research