Direct eNAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling: Transcriptional Regulation by SOX and HIF2 α.

CONCLUSIONS: eNAMPT is a novel and attractive therapeutic target essential to PAH vascular remodeling.
PMID: 32142369 [PubMed - as supplied by publisher]

Source: Mol Biol Cell - March 5, 2020 Category: Molecular Biology Authors: Sun X, Sun BL, Babicheva A, Vanderpool R, Oita RC, Casanova N, Tang H, Gupta A, Lynn H, Gupta G, Rischard F, Sammani S, Kempf CL, Moreno-Vinasco L, Ahmed M, Camp SM, Wang J, Desai AA, Yuan JX, Garcia JGN Tags: Am J Respir Cell Mol Biol Source Type: research