A Fading Vertex Drug Was Also Fastest To Become A Blockbuster

How is this for irony? The same week that Vertex Pharmaceuticals (VRTX) cuts 15 percent of its workforce due to plunging sales of its Incivek treatment for hepatitis C, the drug has been identified as having achieved blockbuster status faster than any other medicine. Incivek was launched in 2011, by the way, and surpassed Celebrex, which is sold by Pfizer (PFE) but was launched in 1999 by Pharmacia. The analysis was conducted by EvaluatePharma which reviewed quarterly US products sales and aggregated the first four full quarters after each drug launch in the region. Only five drugs have ever achieved blockbuster status in their first year on the market – the Vioxx painkiller that was sold and later withdrawn by Merck (MRK); the Victoza diabetes drug sold by Novo Nordisk and Pfizer’s Lipitor cholesterol pill. Each nearly achieved or exceeded $1 billion in sales during that first year. If you are wondering which other drugs were also found to be among the fastest launches, these included Neulasta, an Amgen (AMGN) treatment for white blood cell deficiency; Eyelea, which Regeneron Pharmaceuticals (REGN) sells for macular disorders; the Viagra impotence pill sold by Pfizer; the Lucentis treatment for macular disorders sold by Roche, and the Atripla HIV antiviral sold by Gilead Sciences (GILD). “With an astonishing $420 million in sales booked in its first full quarter on the market, (Incivek) holds another record, and this one at least looks hard to beat,” ...
Source: Pharmalot - Category: Pharma Commentators Authors: Source Type: blogs

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Source: Food Research International - Category: Food Science Source Type: research
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Source: Food Chemistry - Category: Food Science Source Type: research
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Source: Antiviral Therapy - Category: Virology Source Type: research
Florida had 51 hepatitis A cases reported last week, bringing the total number of cases this year to 3,079, as of Saturday. Duval County had the largest number of newly reported cases last week with six, followed by Citrus County with four, according to a News Service of Florida analysis of weekly data from the Florida Department of Health. Pasco, Pinellas and Volusia counties, meanwhile, continue to lead the state in the overall numbers of reported hepatitis A infections with 407,377 and 276 cases,…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Publication date: Available online 18 November 2019Source: Saudi Journal of Biological SciencesAuthor(s): V. Duraipandiyan, R. Balamurugan, Naif Abdullah Al-Dhabi, T. William Raja, P. Ganesan, B. Ahilan, M. Valan Arasu, S. Ignacimuthu, Galal Ali EsmailAbstractBorassus flabellifer L. is a tall palm traditionally used for its stimulating, diuretic and anti-inflammatory activities; it is rich in fibers and various pharmacologically important secondary metabolites. The present study was undertaken to evaluate the antidiabetic effects of Borassus flabellifer fruit methanol extract (BF-M) on diabetic rats induced with High Fat D...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
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Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
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Source: Chinese Journal of Analytical Chemistry - Category: Chemistry Source Type: research
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Source: Technovation - Category: Science Source Type: research
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