Primary antiphospholipid syndrome, Addison disease, and adrenal incidentaloma

We describe an exceptional case of a 23-year-old male patient with APS with persistent high levels of antiphospholipid antibodies (aPL ) from the time of diagnosis, who developed Addison’s disease as a manifestation of APS with atrophy of the adrenal glands, in whom an adrenal incidentaloma was developed later and was corroborated as an aldosterone-producing adenoma. Currently, the patient is asymptomatic and without manifestatio ns of tumor recurrence. The protumoral effect of elevated and persistent aPL is discussed.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research