Prevalence of Children With Complex Chronic Conditions in PICUs of Argentina: A Prospective Multicenter Study*
Conclusions: We observed a high prevalence of patients with complex chronic condition in this sample of argentine PICUs. These patients presented higher mortality and resource use than previously healthy children. This information is valuable to understand the impact that patients with complex chronic condition have on PICU performance and enables proper planning of care.
Milrinone is utilized for hemodynamic support in heart failure (HF) patients. Due to reduced cardiac output and systemic blood flow, patients with HF are at increased risk of thrombosis. Central venous catheter (CVC) placement compounds this risk. The aim of this study was to determine the incidence of thrombosis, identify thrombosis risk factors, and determine the impact of anticoagulation in pediatric patients receiving continuous milrinone via CVC at the Medical University of South Carolina.
The presence of central venous lines (CVLs) post cardiac transplant increases the risk of catheter-associated thromboses (CATs) impacting vascular access. CATs also contribute to the need for prolonged anticoagulation increasing the risk of bleeding and diminished quality of life. Little data exists quantifying the incidence of CATs or associated risk factors after cardiac transplantation in pediatric patients. We aimed to study the incidence of CATs and the impact of a risk-stratified anticoagulation protocol in reducing their development.
Biofilms usually occur on or within medical devices such as mechanical heart valves, prosthetic joints, peritoneal dialysis catheters, contact lenses, central venous catheters, pacemakers and urinary catheters. The presence of biofilms can be seen in different diseases like endocarditis, otitis, cystic fibrosis, periodontitis, osteomyelitis and chronic wounds. Toxin–antitoxin systems are reported to respond to stresses that are also found in the host. Some toxins of toxin–antitoxin systems modules have been proposed as potential weapons used by bacteria to act on host targets. In this review, we focus on the mo...
AbstractVeno-venous extracorporeal membrane oxygenation (VV-ECMO) is a form of extracorporeal life support that provides total gas exchange (CO2 and O2) within the central venous circulation. The bicaval dual lumen cannula (DLC) is an option for patients requiring respiratory support with VV-ECMO. The catheter is inserted via the internal jugular vein into the superior and inferior vena cava, drains blood into the ECMO circuit for gas exchange, and then returns arterialized blood to the right heart for circulation. The DL C facilitates physical therapy, ambulation, and early extubation. This chapter will review the u...
miR-92a-3p and oxidative stress are reportedly associated with venous thrombosis. However, the role of miR-92a-3p and oxidative stress in catheter-related thrombosis (CRT) remains ambiguous. Herein, we studied...
ConclusionUltrasound is a reliable method for detection of CVC positioning. Even so, with the four-chamber cardiac view, this method is unable to identify catheters inside heart chambers, therefore, needing to confirm the positioning with CR.
Patients with hematological malignancies and peripherally inserted central venous catheters (PICCs) tend to develop catheter-associated upper extremity venous thromboses (UEVTs) and pulmonary emboli (PE) [1,2]. Active cancer, malposition and PICC gauge are common risk factors for PICC-UEVTs [2,3]. The association between D-dimer thresholds before catheter insertion and the development of PICC-UEVT in cancer patients remains unknown. D-dimers have been widely used in clinical practice as a high-sensitivity diagnostic approach for suspected venous thromboembolisms (VTEs) .
Conditions: Behavior; Process, Acceptance; Inertia of Accommodation Intervention: Behavioral: targetted implementation strategies Sponsor: Washington University School of Medicine Recruiting
Conditions: Ascites Hepatic; Cirrhosis, Liver; Hypertension, Intraabdominal; Critical Illness; Paracentesis Interventions: Device: continuous drainage of ascitic fluid using an intra-abdominal double lumen central venous catheter; Procedure: Ultrasound-guided intermittent large-volume paracentesis Sponsors: Centro Hospitalar de Lisboa Central; NOVA Medical School Recruiting