Efficacy of Amniotic Membrane Transplantation for the Treatment of Corneal Ulcers

Purpose: To evaluate the outcome of amniotic membrane transplantation (AMTX) as a treatment for corneal ulcers. Methods: Patients treated with AMTX for refractory corneal ulcers between 2012 and 2017 were evaluated in a retrospective analysis. Primary outcome measure was complete reepithelialization. Results: A total of 149 patients were included (mean age 68 ± 18 years). The mean duration between ulcer onset and AMTX was 42 ± 46 days. The longest time between ulcer diagnosis and AMTX was found in bacterial ulcers and the shortest time to AMTX in eyes with trauma/chemical burns (mean 65 ± 15 days and 14 ± 4 days, respectively). In 70% of the patients, a single AMTX procedure was sufficient to achieve epithelial closure (21%
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research