Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects

ConclusionThis study identified a novel SNP of thePOR gene, which affected amlodipine metabolism and may reduce interindividual variation in responses to amlodipine.

Source: Molecular Genetics & Genomic Medicine - March 7, 2020 Category: Genetics & Stem Cells Authors: Ji Min Han, Jeong Yee, Jee Eun Chung, Kyung Eun Lee, Kyungsoo Park, Hye Sun Gwak Tags: ORIGINAL ARTICLE Source Type: research