Nutrigenetics, Metabolic Syndrome Risk and Personalized Nutrition.

Nutrigenetics, Metabolic Syndrome Risk and Personalized Nutrition. Curr Vasc Pharmacol. 2013 Oct 30; Authors: Perez-Martinez P, Phillips CM, Delgado-Lista J, Garcia-Rios A, Lopez-Miranda J, Perez-Jimenez F Abstract The metabolic syndrome (MetS) is a constellation of metabolic risk factors reflecting overnutrition and sedentary lifestyle and its prevalence is increasing dramatically to epidemic proportions. The importance of MetS lies in its close association with the risk of cardiovascular disease and type 2 diabetes. In this scenario, the principal goals of pharmacological therapy for these patients are to achieve and maintain an optimal cardiometabolic control, including lipids, blood glucose and blood pressure; in order to prevent and treat potential complications. Moreover nutrition has commonly been accepted as a cornerstone of treatment for MetS, with the expectation that an appropriate intake of energy and nutrients will improve its control. However the question arises as to whether dietary therapy may require a more personalised approach. In this regard advances in high-throughput genetic analysis have improved our understanding of the contribution of genetics to this diet-related condition. In this review we will present the current state of the art illustrating the significance of gene-nutrient interactions in the context of MetS risk. PMID: 24168447 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research