Differential analysis of serum and urine S100 proteins in juvenile-onset systemic lupus erythematosus (jSLE).

This study demonstrates potential promise for S100A8/A9 and S100A12 as biomarkers for jSLE and active LN. Findings require to be confirmed and tested prospectively in independent and larger multi-ethnic cohorts.
PMID: 32135275 [PubMed - as supplied by publisher]

Source: Clinical Immunology - March 1, 2020 Category: Allergy & Immunology Authors: Donohue SJ, Midgley A, Davies JC, Wright RD, Bruce I, Beresford MW, Hedrich CM, MRC MASTERPLANS Consortium, UK jSLE Cohort Study and Repository Tags: Clin Immunol Source Type: research