Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae.

CONCLUSIONS: Our results demonstrate that the NLRP3 inflammasome is inactive in leprosy, suggesting immune evasion of M. leprae.
PMID: 32130367 [PubMed - as supplied by publisher]

Source: Memorias do Instituto Oswaldo Cruz - March 5, 2020 Category: Infectious Diseases Authors: Mendes ALG, Joaquim HDM, Zamae MIS, Assis RM, Peixoto JRM, de Araújo MMG, Guedes ACM, Oliveira EJ, Magalhães VP, Pascoal-Xavier MA Tags: Mem Inst Oswaldo Cruz Source Type: research