Frequency of CD36 deficiency in Thais analyzed by quantification of CD36 on cell surfaces and in plasma.

CONCLUSION: CD36 Type I deficiency was found, indicating the potential for immune-mediated platelet disorders in Thais. However, the underlying mutations differed from those reported in Japan and China. Interestingly, sCD36 could not be detected in plasma of Type I-deficient individuals. This finding may lead to the use of plasma to identify individuals at risk and to allow screening of large cohorts. PMID: 32129498 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32129498?dopt=Abstract

Source: Transfusion - March 3, 2020 Category: Hematology Authors: Phuangtham R, Santoso S, Leelayuwat C, Komvilaisak P, Ding H, Romphruk AV Tags: Transfusion Source Type: research